Slackness between vessel and myocardium is necessary for coronary flow reserve
نویسندگان
چکیده
منابع مشابه
Slackness between vessel and myocardium is necessary for coronary flow reserve.
Tone regulation in coronary microvessels has largely been studied in isolated vessels in the absence of myocardial tethering. Here, the potential effect of radial tethering and interstitial space connective tissue (ISCT) between coronary microvessels and the surrounding myocardium was studied. We hypothesized that rigid tethering between microvessels and the myocardium would constrain the activ...
متن کاملEvidence for decreased coronary flow reserve in viable postischemic myocardium.
To try to unravel the complexity and heterogeneity of the "no-reflow" phenomenon and its underlying mechanisms, we studied tissue perfusion in reperfused heart muscle by using tracer microspheres in an anesthetized dog model of 90-minute coronary occlusion followed by reperfusion for 2 1/2 hours, 24 hours, or 1 week. Regional myocardial blood flow was determined both in basal flow conditions an...
متن کاملContractile reserve and coronary blood flow reserve in collateral-dependent myocardium.
Numerous studies in recent years have clearly demonstrated that viable myocardium with contractile dysfunction maintains a contractile reserve that can be unmasked by inotropic stimulation, such as by the infusion of low doses of dobutamine. Hence, low-dose dobutamine echocardiography (LDDE) has become firmly established as a diagnostic tool in patients with coronary artery disease (CAD) and le...
متن کاملEVects of coronary revascularisation on myocardial blood flow and coronary vasodilator reserve in hibernating myocardium
Objective—Previous studies have suggested that resting myocardial blood flow is within normal limits in most chronically dysfunctional left ventricular segments which improve function after coronary artery revascularisation (hibernating myocardium). The aim of this study was to assess myocardial blood flow and coronary vasodilator reserve in hibernating myocardium before and after coronary reva...
متن کاملEffects of coronary revascularisation on myocardial blood flow and coronary vasodilator reserve in hibernating myocardium.
OBJECTIVE Previous studies have suggested that resting myocardial blood flow is within normal limits in most chronically dysfunctional left ventricular segments which improve function after coronary artery revascularisation (hibernating myocardium). The aim of this study was to assess myocardial blood flow and coronary vasodilator reserve in hibernating myocardium before and after coronary reva...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2012
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.01184.2011